Organosulfur Compounds
AdipoGen Necrostatin-7 Nec-7
Chemical. CAS 351062-08-3. Formula C16H10FN5OS2. MW 371.4. Necroptosis inhibitor. Does not inhibit RIP1 kinase.
AdipoGen KBU2046
Chemical. CAS 1143863-69-7. Formula C15H11FO2. MW 242.2. Highly selective metastasis inhibitor in vitro. Binds to and stabilizes Cdc37-HSP90beta heterocomplexes, consequently blocking its function and inhibiting cancer cell motility. Does not bind to Cdc37 or HSP90beta alone. Inhibits cancer metastasis in vivo in murine models of human prostate and breast cancer. Shown to exhibit a complete lack of cellular cytotoxicity and systemic toxicity.
AdipoGen KBU2046
Chemical. CAS 1143863-69-7. Formula C15H11FO2. MW 242.2. Highly selective metastasis inhibitor in vitro. Binds to and stabilizes Cdc37-HSP90beta heterocomplexes, consequently blocking its function and inhibiting cancer cell motility. Does not bind to Cdc37 or HSP90beta alone. Inhibits cancer metastasis in vivo in murine models of human prostate and breast cancer. Shown to exhibit a complete lack of cellular cytotoxicity and systemic toxicity.
Selleck Chemical LLC Thioacetamide-E0156-25G
Thioacetamide (TAA) is a hepatotoxin frequently used for experimental purposes which produces centrilobular necrosis after a single dose administration Thioacetamide can be used to induce animal models of Cirrhosis
Sigma Aldrich Fine Chemicals Biosciences Plastic additive 9 United States Pharmacopeia (USP) Reference Standard | 123-28-4 | MFCD00026589 | 100mg
Plastic additive 9 United States Pharmacopeia (USP) Reference StandardPurity: | MW: 510.84 | 123-28-4 | MFCD00026589 | 100mg
eMolecules Medchem Express / MK-571 (sodium) / 5mg / 446270701 / HY-19989A / / 115103-85-0 / MFCD00878420 / 537.060 / C26H26ClN2NaO3S2
Medchem Express / MK-571 (sodium) / 5mg / 446270701 / HY-19989A / / 115103-85-0 / MFCD00878420 / 537.060 / C26H26ClN2NaO3S2
eMolecules 4-Amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide | Combi-Blocks | 122-11-2 | MFCD00057345 | 310.330 | C12H14N4O4S | 98.000 | COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 | 5g | 205386328
4-Amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide | Combi-Blocks | 122-11-2 | MFCD00057345 | 310.330 | C12H14N4O4S | 98.000 | COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 | 5g | 205386328
Sigma Aldrich Fine Chemicals Biosciences Plastic additive 10 United States Pharmacopeia (USP) Reference Standard | 693-36-7 | MFCD00026684 | 100mg
Plastic additive 10 United States Pharmacopeia (USP) Reference Standard | MW: 683.16 | 693-36-7 | MFCD00026684 | 100mg
Medchemexpress LLC Diphenyl disulfide | 882-33-7 | MFCD00003065 | 100.0% | 218.35 g/mol | C12H10S2 | 5g
Diphenyl disulfide is an endogenous metabolite Diphenyl disulfide is a pharmaceutical intermediate Diphenyl disulfide can be coupled with aryl iodide to synthesize asymmetric aryl sulfide[1][2]
Medchemexpress LLC Rat IgG1 kappa Isot 5mg | 5mg
Rat IgG1 kappa Isotype Control a rat monoclonal antibody is an isotype control for Rat IgG1 antibody
Medchemexpress LLC Sirtuin modulator 3 50mg | 50mg
Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative acts as a sirtuin modulator[1]
Biomatik Corporation Glucose Oxidase, 100U/MG. Grade High Purity. Storage -20C. CAS 9001-37-0
Glucose Oxidase, 100U/MG. Grade High Purity. Storage -20C. CAS 9001-37-0
Medchemexpress LLC NX-2127 | 2416131-46-7 | C39H45N9O5 | 200 MG
Zelebrudomide (NX-2127) is an orally active PROTAC degrader targeting Bruton's Tyrosine Kinase (Btk). It effectively inhibits proliferation of BTKC481S mutant TMD8 cells and catalyzes degradation of Ikaros (IKZF1) and Aiolos (IKZF3). It also stimulates T cell activation and increases IL-2 production.
- Orally active PROTAC degrader.
- Targets Bruton's tyrosine kinase (Btk).
- Inhibits BTKC481S mutant TMD8 cell proliferation (EC50 <30 nM).
- Catalyzes Ikaros (IKZF1) and Aiolos (IKZF3) degradation.
- Stimulates T cell activation; increases IL-2 production.
- Potent BTK degradation in cynomolgus monkeys in vivo.
- Superior tumor growth inhibition in WT TMD8 and C481S mutant xenograft models.
- Appearance: solid, light yellow to yellow.
- Purity: 99.72%.